A new quinone propionic acid-cloaked rhodamine fluorophore has its fluorescence revealed (de-cloaked) upon activation by human NAD(P)H:quinone oxidoreductase 1 (hNQO1), an upregulated enzyme in cancer cells and tumors. © 2011 The Royal Society of Chemistry
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron red...
A frontier area in the development of activatable (turn-on) fluorescence-based probes is that concer...
Fluorescence molecular imaging is an emerging field with potential to aid in optically guided surger...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
© 2015 American Chemical Society. Achieving highly selective and sensitive detection/visualization o...
We successfully synthesized a fluorescent probe capable of detecting the cancer-associated NAD(P)H...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
Enzyme-responsive probes, whose fluorescence signature is selectively and uniquely changed upon acti...
NAD(P)H quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two electron reduc-tion...
Fast, selective, and noninvasive reporting of intracellular cancer-associated events and species wil...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron red...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron red...
A frontier area in the development of activatable (turn-on) fluorescence-based probes is that concer...
Fluorescence molecular imaging is an emerging field with potential to aid in optically guided surger...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
© 2015 American Chemical Society. Achieving highly selective and sensitive detection/visualization o...
We successfully synthesized a fluorescent probe capable of detecting the cancer-associated NAD(P)H...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
Achieving the vision of identifying and quantifying cancer-related events and targets for future per...
Enzyme-responsive probes, whose fluorescence signature is selectively and uniquely changed upon acti...
NAD(P)H quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two electron reduc-tion...
Fast, selective, and noninvasive reporting of intracellular cancer-associated events and species wil...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron red...
Abstract: Two-electron reduction of quinones catalyzed by NAD(P)H:quinone oxidoreductase (NQO1) prot...
An extensive body of evidence supports the conclusion that by catalyzing obligatory two-electron red...
A frontier area in the development of activatable (turn-on) fluorescence-based probes is that concer...