Medicinal Plants Used in the Treatment of Cardiovascular Disorders in the Czech Republic - Overview and Consumption Analysis in Years 2015 - 2019

Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy Candidate RNDr. Mgr. Marianna Dubánková Consultant doc. Ing. Kateřina Macáková, PhD. Title of Thesis Medicinal Plants Used in the Treatment of Cardiovascular Disorders in the Czech Republic - Overview and Consumption Analysis in Years 2015 - 2019. Medicinal plants still hold their strong position in the therapy of various human diseases, even in the modern era. Seven medicinal plants long known for their use in the treatment of cardiovascular disorders were chosen for this thesis, namely Allium sativum L. (garlic), Crataegus spp. (hawthorn), Digitalis spp. (foxglove), Leonurus cardiaca L. (motherwort), Olea europaea L. (olive), Nigella sativa L. (black cumin), and Viscum album L. (European mistletoe). Their beneficial effects on the cardiovascular system (antioxidant, cardioprotective, vasorelaxant, antiatherosclerotic, antihypertensive, and lipid-lowering actions) were reviewed with an emphasis on information concerning humans. When possible, the mechanism explanation, results of clinical trials, and established dosage range for the respective fields of action are presented. The consumption analysis of the preparations containing the abovementioned medicinal plants was conducted with a total number of..