This diploma thesis deals with pressure losses in heating systems. The diploma thesis is divided into three sections. The first part is theoretical and deals with the occurrence of pressure losses. It discusses the properties of the fluid that affect pressure losses. It also deals with hydrodynamic phenomena, flow distribution, pressure loss distribution and its calculations. The aim of the second part, which is practical, was to create a heating project for a selected object. The object is a two-floor kindergarten building located in Velké Němčice. For this project, two heating variants were created. For the first variant, radiators and heating benches were designed and for the second variant, underfloor heating was installed in the buildi...