There is one report about the crystallization of a membrane-anchored protein. However, the crystals of the hydrophilic domain alone, which could also be obtained, are of a much better quality. This chapter discusses purity, homogeneity, and stability of membrane proteins are the most important prerequisites for their crystallization. The most suited starting materials for membrane protein isolation are specialized biological membranes, where certain membrane proteins are considerably enriched. One of the worst obstacles in membrane protein crystallization is the detergent's tendency to form a separate, viscous detergent phase. This detergent phase is formed upon the addition of precipitants and/or temperature shifts and contains the membran...
Obtaining well-ordered crystals is a major hurdle to X-ray structure determination of membrane prote...
Phase separation is a simple, efficient, and cheap method to purify and concentrate detergent-solubi...
This review summarizes the present literature on two-dimensional crystallization of membrane protein...
To the uninitiated, the process of crystallizing a membrane protein may appear rather daunting, due ...
The need for high-resolution structure information on membrane proteins is immediate and growing. Cu...
When starting a protein-crystallization project, scientists are faced with several unknowns. Amongst...
After a long period of fruitless attempts, three-dimensional crystal of membrane proteins are now av...
AbstractAs a first step toward the establishment of practical guidelines for the search for crystall...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
Studying membrane proteins represents a major challenge in protein biochemistry, with one of the maj...
AbstractStructure determination at high resolution is actually a difficult challenge for membrane pr...
Studying membrane proteins represents a major challenge in protein biochemistry, with one of the maj...
AbstractStudying membrane proteins represents a major challenge in protein biochemistry, with one of...
Obtaining well-ordered crystals is a major hurdle to X-ray structure determination of membrane prote...
Phase separation is a simple, efficient, and cheap method to purify and concentrate detergent-solubi...
This review summarizes the present literature on two-dimensional crystallization of membrane protein...
To the uninitiated, the process of crystallizing a membrane protein may appear rather daunting, due ...
The need for high-resolution structure information on membrane proteins is immediate and growing. Cu...
When starting a protein-crystallization project, scientists are faced with several unknowns. Amongst...
After a long period of fruitless attempts, three-dimensional crystal of membrane proteins are now av...
AbstractAs a first step toward the establishment of practical guidelines for the search for crystall...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
To study integral membrane proteins, one has to extract them from the membrane—the step that is typi...
Studying membrane proteins represents a major challenge in protein biochemistry, with one of the maj...
AbstractStructure determination at high resolution is actually a difficult challenge for membrane pr...
Studying membrane proteins represents a major challenge in protein biochemistry, with one of the maj...
AbstractStudying membrane proteins represents a major challenge in protein biochemistry, with one of...
Obtaining well-ordered crystals is a major hurdle to X-ray structure determination of membrane prote...
Phase separation is a simple, efficient, and cheap method to purify and concentrate detergent-solubi...
This review summarizes the present literature on two-dimensional crystallization of membrane protein...