Neutrophil/lymphocyte and platelet/lymphocyte ratios are associated with disease activity in rheumatoid arthritis

Aim: The aim of this study is to determine the relationship between Neutrophil to Lymphocyte (NLR) and Platelet to Lymphocyte (PLR) ratios in patients with Rheumatoid Arthritis (RA) and Disease Activity Score-28 (DAS28) and Rheumatoid Arthritis Quality of We (RAQoL). Material and Method: One hundred twenty-five RA patients and 105 healthy controls were enrolled in the study. Patients were assessed and PLR, NLR, and DAS28, RAQoL values were calculated. Disease activity was calculated by DAS28 and quality of life was examined by RAQoL, HAQ (Health Assessment Questionnaire). Results: NLR (2,4 +/- 1,9) and PLR (155,2 +/- 82,3) value was significantly higher (p 0,05). Discussion: This study presents that NLR and PLR are associated with disease activity in patients with RA. NLR and PLR values can be assessed as an additional inflammatory marker in patients with RA