The Relatıonshıp between Helıcobacter Pylorı Infectıon and Glycemıc Regulatıon in Type 2 Dıabetıc Patıents

THE RELATIONSHIP BETWEEN HELICOBACTER PYLORI INFECTION AND GLYCEMIC REGULATION IN TYPE 2 DIABETIC PATIENTS Seydahmet Akın, Muhammet Emin Erdem, Sinan Kazan, Mehmet Aliustaoğlu  ABSTRACTObjective: We evaluated the relationship between Helicobacter pylori (HP) positivity and glycemic regulation in type 2 diabetic patients. Material and Method: 315 type 2 diabetic patients admitted to Dr. Lütfi Kirdar Kartal Training and Research Hospital Internal Medicine Polyclinics were evaluated retrospectively. Fasting plasma glucose, HbA1c levels and urea breath test (UBT) results were analyzed. The relationship between HbA1c levels and UBT positivity were investigated. Results: Fasting plasma glucose was significantly higher in UBT positive patients (175.3±73.9 mg/dl ) than in UBT negative patients (139.3±35.6 mg/dl) (p<0.05). HbA1c levels were also detected as significantly higher in UBT positive patients (8.0±2.1) than in the UBT negative ones (6.9±1.2) (p<0.05). Conclusion: We showed in our study that HP infection rates detected with UBT in diabetic patients are significantly higher in patients with poor glycemic control than in the ones with tight glycemic control.  Keywords: Diabetes mellitus, Helicobacter pylori, HbA1c Nobel Med 2014; 10(3): 32-35