Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder that exhibits a common set of behavioral and cognitive impairments. Although the etiology of ASD remains unclear, mitochondrial dysfunction has recently emerged as a possible causative factor underlying ASD. The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that augments mitochondrial function, and has been shown to reduce autistic behaviors in both humans and in rodent models of ASD. The aim of the current study was to examine mitochondrial bioenergetics in the BTBR mouse model of ASD and to determine whether the KD improves mitochondrial function. We also investigated changes in mitochondrial morphology, which can directly influence mitochondrial f...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Abstract: Classical mitochondrial diseases occur in a subset of individuals with autism and are usua...
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder that exhibits a com...
The ketogenic diet (KD) has been utilized as a dietary therapeutic for nearly a century. One experim...
The ketogenic diet (KD) has been utilized as a dietary therapeutic for nearly a century. One experim...
Autism spectrum disorder (ASD) is characterized by deficits in sociability and communication, and in...
In the last decade, research interest has focused on understanding the etiology and pathogenesis of ...
BackgroundGastrointestinal dysfunction and gut microbial composition disturbances have been widely r...
BackgroundGastrointestinal dysfunction and gut microbial composition disturbances have been widely r...
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and ...
The role of the liver in autism spectrum disorders (ASD), developmental disabilities characterized b...
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and ...
Autism spectrum disorder (ASD) is characterized by deficits in sociability and communication, and in...
Stereotypic behaviors are repetitive, invariant, and purposeless actions resulting from central nerv...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Abstract: Classical mitochondrial diseases occur in a subset of individuals with autism and are usua...
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder that exhibits a com...
The ketogenic diet (KD) has been utilized as a dietary therapeutic for nearly a century. One experim...
The ketogenic diet (KD) has been utilized as a dietary therapeutic for nearly a century. One experim...
Autism spectrum disorder (ASD) is characterized by deficits in sociability and communication, and in...
In the last decade, research interest has focused on understanding the etiology and pathogenesis of ...
BackgroundGastrointestinal dysfunction and gut microbial composition disturbances have been widely r...
BackgroundGastrointestinal dysfunction and gut microbial composition disturbances have been widely r...
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and ...
The role of the liver in autism spectrum disorders (ASD), developmental disabilities characterized b...
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and ...
Autism spectrum disorder (ASD) is characterized by deficits in sociability and communication, and in...
Stereotypic behaviors are repetitive, invariant, and purposeless actions resulting from central nerv...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Mitochondrial dysfunction is a major cause of neurodegenerative and neuromuscular diseases of adult ...
Abstract: Classical mitochondrial diseases occur in a subset of individuals with autism and are usua...