Compliance with bladder protocol during concurrent chemoradiation for cancer of the cervix and its impact on enteritis: A prospective observational study

AimThis prospective study aims to assess the compliance with bladder protocol and the correlation with enteritis during pelvic radiation.BackgroundBladder protocol is routinely used for patients undergoing pelvic radiation to reduce radiation enteritis. It is very difficult to maintain constant volume especially in the last two weeks due to radiation enteritis and cystitis.Materials and methodsHistologically proven 35 cervical cancer patients treated with concurrent chemoradiation in a tertiary care center were the subjects of this prospective study. Following CT simulation and after every fraction, patients were asked to void urine in a calibrated urine container and the volume was documented. Patients were assessed for the highest grade of radiation enteritis weekly as per common toxicity criteria. The mean voided urine volume was correlated with the radiation enteritis.ResultsThe mean urine volume at planning CT scan was 295.85[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]300[[ce:hsp sp="0.25"/]]ml (SD) with a range of 75–650. At the end of treatment, it was reduced to 233.14[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]250[[ce:hsp sp="0.25"/]]ml (range 50–400[[ce:hsp sp="0.25"/]]ml), a reduction by 21% (p[[ce:hsp sp="0.25"/]