There are no established dosimetry tools to predict toxicity of “targeted alpha-therapy” (TAT), yet. We conducted an empiric dose escalation to find the maximum tolerable dose (MTD) of single cycle and fractionation concepts for Ac-225-DOTATOC radionuclide therapy.JRC.E.5-Nuclear chemistr
Targeted alpha therapy (TAT) is a promising approach for the treatment of cancer. The use of alpha e...
IMPORTANCE Targeted alpha therapy attempts to deliver systemic radiation selectively to cancer cells...
Abstract Background Actinium-225 is an alpha-particle emitter under investigation for use in radioph...
Objectives: There are no established dosimetry tools to predict toxicity of “targeted alpha-therapy”...
Targeted alpha therapy (TAT) is a novel approach for the treatment of cancer and infectious diseases...
Peptide receptor radionuclide therapy (PRRT) using somatostatin analogues labeled with beta-particle...
Ziel/ Aim Alpha-particle emitters display high linear energy transfer combined with short range and ...
The effectiveness of targeted α-therapy (TAT) can be explained by the properties of α-particles. Alp...
The use of targeted ligands to deliver radioisotopes directly to tumor cells is a promising therapeu...
Targeted alpha therapy (TAT) is showing promise in the treatment of solid and liquid tumors. TAT use...
Alpha-particle emitter radiopharmaceutical therapy (alpha-RPT) is a promising approach to cancer the...
Radiopharmaceuticals have been used for the treatment of various forms of cancer since the 1940s. In...
Metastatic disease requires a systemic approach to therapy. Alpha particle radiopharmaceutical thera...
Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical...
The objective of dosimetry is to guide the design and implementation of radiopharmaceutical therapy,...
Targeted alpha therapy (TAT) is a promising approach for the treatment of cancer. The use of alpha e...
IMPORTANCE Targeted alpha therapy attempts to deliver systemic radiation selectively to cancer cells...
Abstract Background Actinium-225 is an alpha-particle emitter under investigation for use in radioph...
Objectives: There are no established dosimetry tools to predict toxicity of “targeted alpha-therapy”...
Targeted alpha therapy (TAT) is a novel approach for the treatment of cancer and infectious diseases...
Peptide receptor radionuclide therapy (PRRT) using somatostatin analogues labeled with beta-particle...
Ziel/ Aim Alpha-particle emitters display high linear energy transfer combined with short range and ...
The effectiveness of targeted α-therapy (TAT) can be explained by the properties of α-particles. Alp...
The use of targeted ligands to deliver radioisotopes directly to tumor cells is a promising therapeu...
Targeted alpha therapy (TAT) is showing promise in the treatment of solid and liquid tumors. TAT use...
Alpha-particle emitter radiopharmaceutical therapy (alpha-RPT) is a promising approach to cancer the...
Radiopharmaceuticals have been used for the treatment of various forms of cancer since the 1940s. In...
Metastatic disease requires a systemic approach to therapy. Alpha particle radiopharmaceutical thera...
Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical...
The objective of dosimetry is to guide the design and implementation of radiopharmaceutical therapy,...
Targeted alpha therapy (TAT) is a promising approach for the treatment of cancer. The use of alpha e...
IMPORTANCE Targeted alpha therapy attempts to deliver systemic radiation selectively to cancer cells...
Abstract Background Actinium-225 is an alpha-particle emitter under investigation for use in radioph...