Unprecedented Incorporation of alpha-Emitter Radioisotope 213Bi into Porphyrin Chelates with Reference to a Daughter Isotope Mediated Assistance Mechanism
- LE GAC Stephane
- NAJJARI Btissam
- MOTREFF Nicolas
- REMAUD-LE SAEC Patricia
- FAIVRE-CHAUVET A
- DIMANCHE-BOITREL M
- MORGENSTERN Alfred
- BRUCHERTSEIFER Frank
- LACHKAR M
- BOITREL Bernard
Publication date
June 2011
DOI Publisher
Royal Society of Chemistry (RSC) Journal
Chemical CommunicationsAbstract
For the first time, alphaemitter radioisotope 213Bi has been 10 incorporated into porphyrin chelates, with rates matching with the short period of the radionuclide. An in-situ transmetalation mechanism involving the daughter isotope 209Pb is expected to boost the 213Bi radiolabeling process.JRC.E.5-Nuclear chemistr
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