Increasing public concern about the use of large numbers of animals in the safety evaluation of new chemicals and products has contributed, in part, to the development and evaluation of various non-animal methods in recent years. Several of these have been proposed as possible replacements for some of the animal procedures currently required in regulatory toxicity testing. In toxicological research, there has been a significant move away from whole animal studies, largely because of the application of cellular and molecular biology techniques. The development of appropriate in vitro test systems has enabled mechanistic studies to be undertaken, which cannot readily be carried out in living animals.JRC.(EI)-Environment Institut
During the development of potential new medicines or agrochemicals, an assessment of the safety prof...
The need for alternative approaches to the use of vertebrate animals for hazard assessing chemicals ...
Acute systemic toxicity testing provides the basis for hazard labeling and risk management of chemic...
Biomedical endeavours can be divided into three major categories: research, education, and testing. ...
Laboratory animal models are limited by scientific constraints on human applicability, and increasin...
Alternative approaches to animal testing are gaining momentum with an increasing number of test meth...
EU regulations call for the use of alternative methods to animal testing. During the last decade, an...
Due to public pressure, in vivo methods of toxicity testing is being attempted to be replaced by in ...
AbstractThe number of animals used in research has increased with the advancement of research and de...
Alternatives to animal experimentation are highly touted today by animal welfare advocates. Their ca...
In the past few years, many in vitro methods for animal toxicity testing have been developed, valida...
There is growing public pressure to minimize the use of vertebrates in ecotoxicity testing; therefor...
With rapidly increasing knowledge of toxicological processes, the scientific value and relevance of ...
Alternative approaches to animal testing are gaining momentum with an increasing number of test meth...
Animal experimentation is an emotional topic, which arouses passionate feelings both in animal prote...
During the development of potential new medicines or agrochemicals, an assessment of the safety prof...
The need for alternative approaches to the use of vertebrate animals for hazard assessing chemicals ...
Acute systemic toxicity testing provides the basis for hazard labeling and risk management of chemic...
Biomedical endeavours can be divided into three major categories: research, education, and testing. ...
Laboratory animal models are limited by scientific constraints on human applicability, and increasin...
Alternative approaches to animal testing are gaining momentum with an increasing number of test meth...
EU regulations call for the use of alternative methods to animal testing. During the last decade, an...
Due to public pressure, in vivo methods of toxicity testing is being attempted to be replaced by in ...
AbstractThe number of animals used in research has increased with the advancement of research and de...
Alternatives to animal experimentation are highly touted today by animal welfare advocates. Their ca...
In the past few years, many in vitro methods for animal toxicity testing have been developed, valida...
There is growing public pressure to minimize the use of vertebrates in ecotoxicity testing; therefor...
With rapidly increasing knowledge of toxicological processes, the scientific value and relevance of ...
Alternative approaches to animal testing are gaining momentum with an increasing number of test meth...
Animal experimentation is an emotional topic, which arouses passionate feelings both in animal prote...
During the development of potential new medicines or agrochemicals, an assessment of the safety prof...
The need for alternative approaches to the use of vertebrate animals for hazard assessing chemicals ...
Acute systemic toxicity testing provides the basis for hazard labeling and risk management of chemic...