Add to ORKGThe MAP kinase p38 is implicated in the release of the pro-inflammatory cytokines TNF-α and IL-1β. Inhibition of cytokine release may be a useful treatment for inflammatory conditions such as rheumatoid arthritis and Crohn\u27s disease. A novel series of imidazopyrimidines have been discovered that potently inhibit p38 and suppress the production of TNF-α in vivo
p38α MAPK is an intracellular serine/threonine protein kinase that regulates many physiological proc...
Signal transduction through the p38 mitogen-activated protein (MAP) kinase pathway is central to the...
COT kinase (TPl2, MAP3K8) is an important regulator of the pro-inflammatory cytokines TNFalpha and I...
The MAP kinase p38 is implicated in the release of the pro-inflammatory cytokines TNF-α and IL-1β. I...
The MAP kinase p38 plays a key role in the biosynthesis of the inflammatory cytokines TNF-α and IL-1...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
The trigger and etiology of chronic inflammatory diseases are not well understood, hindering the dev...
RPR132331, a 2-(2-dioxanyl)imidazole, was identified as an inhibitor of tumour necrosis factor (TNF)...
p38α MAPK is an intracellular serine/threonine protein kinase that regulates many physiological proc...
A library of trisubstituted oxazoles, thiazoles, imidazoles (1,2,4- and 2,4,5-substituted) and imida...
p38α MAPK is an intracellular serine/threonine protein kinase that regulates many physiological proc...
Signal transduction through the p38 mitogen-activated protein (MAP) kinase pathway is central to the...
COT kinase (TPl2, MAP3K8) is an important regulator of the pro-inflammatory cytokines TNFalpha and I...
The MAP kinase p38 is implicated in the release of the pro-inflammatory cytokines TNF-α and IL-1β. I...
The MAP kinase p38 plays a key role in the biosynthesis of the inflammatory cytokines TNF-α and IL-1...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
Inhibition of the p38 map kinase pathway has been shown to be beneficial in the treatment of inflamm...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
P38α/MAPK14 is intracellular signalling regulator involved in biosynthesis of inflammatory mediator ...
The trigger and etiology of chronic inflammatory diseases are not well understood, hindering the dev...
RPR132331, a 2-(2-dioxanyl)imidazole, was identified as an inhibitor of tumour necrosis factor (TNF)...
p38α MAPK is an intracellular serine/threonine protein kinase that regulates many physiological proc...
A library of trisubstituted oxazoles, thiazoles, imidazoles (1,2,4- and 2,4,5-substituted) and imida...
p38α MAPK is an intracellular serine/threonine protein kinase that regulates many physiological proc...
Signal transduction through the p38 mitogen-activated protein (MAP) kinase pathway is central to the...
COT kinase (TPl2, MAP3K8) is an important regulator of the pro-inflammatory cytokines TNFalpha and I...