This paper asks whether prioritarianism – the view that social welfare orderings should give explicit priority to the worse-off – is consistent with the normative theory of equality of opportunity. We show that there are inherent tensions between some of the axioms underpinning prioritarianism and the principles underlying equality of opportunity; but also that these inconsistencies vanish under plausible adjustments to the domains of two key axioms, namely anonymity and the transfer principle. That is: reconciling prioritarianism and equality of opportunity is possible but allowing room for individual responsibility within prioritarianism requires compromises regarding the nature and scope of both impartiality and inequality aversion. The ...