The mature cerebellum controls motor skill precision and participates in other sophisticated brain functions that include learning, cognition, and speech. Different types of GABAergic and glutamatergic cerebellar neurons originate in temporal order from two progenitor niches, the ventricular zone and rhombic lip, which express the transcription factors Ptf1a and Atoh1, respectively. However, the molecular machinery required to specify the distinct neuronal types emanating from these progenitor zones is still unclear. Here, we uncover the transcription factor Olig3 as a major determinant in generating the earliest neuronal derivatives emanating from both progenitor zones in mice. In the rhombic lip, Olig3 regulates progenitor cell proliferat...
In the postnatal forebrain regionalized neural stem cells along the ventricular walls produce olfact...
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and ind...
Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learn...
peer reviewedThe mature cerebellum controls motor skill precision and participates in other sophist...
The mature cerebellum controls motor skill precision and participates in other sophisticated brain f...
The cerebellum is critical for motor functions such as coordination, precision and accurate timing o...
We present histological and molecular analyses of the developing human cerebellum from 30 days after...
In the developing mammalian central nervous system, the basal forebrain produces various kinds of n...
The Olig3 gene encodes a bHLH factor that is expressed in the ventricular zone of the dorsal alar pl...
AbstractThe oligodendrocyte lineage genes Olig1 and Olig2 encode related bHLH proteins that are coex...
The assembly of neural circuits involves multiple sequential steps such as the specification of cell...
AbstractOLIG1 and OLIG2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the pMN...
Oligodendrocyte progenitor cells (OPCs) are immature cells in the central nervous system (CNS) that ...
Brain development is a complex process requiring precise coordination of molecular processes across ...
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). By enabling rapid n...
In the postnatal forebrain regionalized neural stem cells along the ventricular walls produce olfact...
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and ind...
Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learn...
peer reviewedThe mature cerebellum controls motor skill precision and participates in other sophist...
The mature cerebellum controls motor skill precision and participates in other sophisticated brain f...
The cerebellum is critical for motor functions such as coordination, precision and accurate timing o...
We present histological and molecular analyses of the developing human cerebellum from 30 days after...
In the developing mammalian central nervous system, the basal forebrain produces various kinds of n...
The Olig3 gene encodes a bHLH factor that is expressed in the ventricular zone of the dorsal alar pl...
AbstractThe oligodendrocyte lineage genes Olig1 and Olig2 encode related bHLH proteins that are coex...
The assembly of neural circuits involves multiple sequential steps such as the specification of cell...
AbstractOLIG1 and OLIG2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the pMN...
Oligodendrocyte progenitor cells (OPCs) are immature cells in the central nervous system (CNS) that ...
Brain development is a complex process requiring precise coordination of molecular processes across ...
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). By enabling rapid n...
In the postnatal forebrain regionalized neural stem cells along the ventricular walls produce olfact...
The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and ind...
Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learn...