Antimicrobial Resistance is a fundamental threat to global health and safety” (WHO, 2016). Nisin, a 34 amino acid lanthipeptide, is currently used as a food preservative worldwide and has been used for decades without significant bacterial resistance having developed. It is an extremely active molecule which kills a range of different bacterial species. However nisin, along with some other similar peptides, suffers from low stability and solubility at physiological pH, which severely restricts its possible use in human and veterinary medicine. This research is concerned with increasing the stability of nisin in physiological pH systems; the stability of the dehydroalanine (Dha) at position 33 was examined as one of the project aims, along w...
The resistance of pathogens to traditional antibiotics enforces people to search for new antimicrobi...
As microorganisms continue to develop resistance and survive against many different forms of antimic...
Nisin A is a potent antimicrobial with potential as an alternative to traditional antibiotics, and a...
Antimicrobial Resistance is a fundamental threat to global health and safety” (WHO, 2016). Nisin, a ...
Nisin is a 3.4-kDa antimicrobial peptide that, as a result of posttranslational modifications, conta...
The global concern over the emergence of antibiotic-resistant pathogens is growing, demanding for ne...
peer-reviewedIt is becoming increasingly apparent that innovations from the “golden age” of antibiot...
peer reviewedNisin P is a natural nisin variant, the genetic determinants for which were previously ...
The emergence and dissemination of antibiotic resistant bacteria is a major medical challenge. Lanti...
Nisin A is the most thoroughly investigated member of the lantibiotic family of antimicrobial peptid...
Nisin, a 34-residue peptide bacteriocin, contains the less common amino acids lanthionine, β-methyll...
The pentacyclic peptide antibiotic nisin, produced by Lactococcus lactis is ubiquitously applied as ...
Noncanonical amino acids form a highly diverse pool of building blocks that can render unique physic...
Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and...
The resistance of pathogens to traditional antibiotics enforces people to search for new antimicrobi...
As microorganisms continue to develop resistance and survive against many different forms of antimic...
Nisin A is a potent antimicrobial with potential as an alternative to traditional antibiotics, and a...
Antimicrobial Resistance is a fundamental threat to global health and safety” (WHO, 2016). Nisin, a ...
Nisin is a 3.4-kDa antimicrobial peptide that, as a result of posttranslational modifications, conta...
The global concern over the emergence of antibiotic-resistant pathogens is growing, demanding for ne...
peer-reviewedIt is becoming increasingly apparent that innovations from the “golden age” of antibiot...
peer reviewedNisin P is a natural nisin variant, the genetic determinants for which were previously ...
The emergence and dissemination of antibiotic resistant bacteria is a major medical challenge. Lanti...
Nisin A is the most thoroughly investigated member of the lantibiotic family of antimicrobial peptid...
Nisin, a 34-residue peptide bacteriocin, contains the less common amino acids lanthionine, β-methyll...
The pentacyclic peptide antibiotic nisin, produced by Lactococcus lactis is ubiquitously applied as ...
Noncanonical amino acids form a highly diverse pool of building blocks that can render unique physic...
Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and...
The resistance of pathogens to traditional antibiotics enforces people to search for new antimicrobi...
As microorganisms continue to develop resistance and survive against many different forms of antimic...
Nisin A is a potent antimicrobial with potential as an alternative to traditional antibiotics, and a...