A Rod-Shaped Guest Leads to Architectural Isomerism in a Multicomponent Crystalline Framework Based on a Resorcin[4]arene

Cocrystallization of C-methylcalix[4]resorcinarene 1 with 4,4'-bipyridine 2 in the presence of 4-bromobiphenyl (4-brbp) yields a molecular solid, of composition 3d?(4-brbp), [where 3d = 1?2(2)], in which 1 assembles with 2 to form a one-dimensional hydrogen-bonded polymer 3d that includes two copies of the biphenyl, within elliptical cavities of dimensions ~ 11 ? 7 ? 6 ?, as guests. The framework 3d represents a third architectural isomer of three previously reported supramolecular isomers of the parent material 3.NRC publication: Ye