Uncertainties for upper-air trend patterns are still substantial. Observations from the radio occultation (RO) technique offer new opportunities to assess the existing observational records there. Long-term time series are available from radiosondes and from the (Advanced) Microwave Sounding Unit (A)MSU. None of them were originally intended to deliver data for climate applications. Demanding intercalibration and homogenization procedures are required to account for changes in instrumentation and observation techniques. In this comparative study three (A)MSU anomaly time series and two homogenized radiosonde records are compared to RO data from the CHAMP, SAC-C, GRACE-A and F3C missions for September 2001 to December 2009. Differences of mo...