Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Large evolutionary distances imply a large number of homoplastic sites. As most protein-coding genes show dramatic variations in substitution rates that are not uncorrelated across the sequence, this often leads to a patchwork pattern of (i) phylogenetically informative and (ii) effectively randomized regions. In highly variable regions, furthermore, alignment errors accumulate resulting in sometimes misleading signals in phylogenetic reconstruction. Results: We present here a method that, based on assessing the distribution of character states along a cyclic ordering...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
International audienceBACKGROUND:The quality of multiple sequence alignments plays an important role...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
Motivation Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
International audienceBACKGROUND:The quality of multiple sequence alignments plays an important role...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Molecular evolutionary biology allows us to look into the past by analyzing sequences of amino acids...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...