Synthesis and photophysics behaviour in AOT/cyclohexane w/o microemulsions of a new benzo[a]phenoxazinium chloride with 3-((3-chloropropyl)disulfanyl)propyl)amino group

Fluorescent probes for labelling of biomolecules are widely used for various purposes. In this context we have efficiently synthesised a new benzo[a]phenoxazinium chloride possessing the 3-((3-chloropropyl)disulfanyl)propyl)amino group at position 5. The disulfide bond can be cleaved under mild basic conditions to afford the free thiol group, and consequently this heterocycle could act as a capping layer for the passivation of semiconductor QDs. The location of the new benzo[a]phenoxazinium chloride in AOT/cyclohexane was studied by fluorescence spectroscopy, since this microheterogeneous structures are frequently used for nanoparticle synthesis.Fundação para a Ciência e Tecnologia (FCT, Portugal) for financial support to the NMR portuguese network (PTNMR, Bruker Avance III 400-Univ. Minho), FCT and FEDER (European Fund for Regional Development)-COMPETE-QREN-EU for financial support to the Research Centres CFUM [PEst-C/FIS/UI0607/2011 (F-COMP-01-0124-FEDER-022711)] and CQ/UM [PEst-C/QUI/UI0686/2011 (FCOMP-01-0124-FEDER-022716)]. A post-doctoral grant to B. R. Raju (SFRH/BPD/62881/2009) is also financed by FCT, POPH-QREN, FSE