Disseminated Infections with Talaromyces marneffei in Non-AIDS Patients Given Monoclonal Antibodies against CD20 and Kinase Inhibitors

Lam, FYF
Singh, GHH
Chan, TSY
Chan, JFW
Lau, SKP
Tse, H
Trendell-Smith, NJ
Woo, PCY
Yuen, KY
Hung, IFN
Sridhar, S

Open link

Publication date

January 2015

DOI

10.3201/eid2107.150138

Publisher

Centers for Disease Control and Prevention (CDC)

ISSN

1080-6040

Journal

issn:1080-6040

Citation count (estimate)

Abstract

Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal antibodies against CD20 or kinase inhibitors during the past 2 years. Clinicians should be aware of this emerging complication, especially in patients from disease-endemic regions.link_to_OA_fulltex