Add to ORKGThe present invention pertains to Cimiracemate A and related compounds that are useful as inhibitors of 5-lipoxygenase (5-1. OX) activity and various proinflammatory mediators such as lipoxins, leukotrienes (e.g., LTA4, LTB4, LTC4, LTD4, and LTE4), prostaglandins, and thromboxanes. The present invention also provides therapeutic methods and compositions for treatment of inflammation and inflammatory conditions, including allergenic reactions, diseases associated with cell proliferation, neoangiogenesis, and cardiovascular diseases.published_or_final_versio
The present invention relates to the field of pharmaceuticals. In particular, it relates to new com...
Cimicifuga species have been used as traditional medicinal herbs to treat inflammation and symptoms ...
Novel esters of non steroidal anti-inflammatory drugs, α-lipoic acid and indol-3-acetic acid with ci...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
The subject invention provides a method for optimal isolation of cimiracemate A for subsequent use a...
A series of lumiracoxib derivatives were designed to explore the influence of isosteric substitution...
Drugs able to inhibit both cyclooxygenases (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) (dual acting...
Inflammation is a complex phenomenon that results as a healing response of organisms to different fa...
The subject invention provides novel and advantageous materials and methods for treating neuroinflam...
A method for treating inflammatory and immune conditions by modulating TNF-a and nitric oxide produc...
A method for treating inflammatory and immune conditions by modulating TNF-[alpha] and nitric oxide ...
Inflammatory mediators are local hormones that act via specific cell-surface receptors in an autocri...
The present invention relates to the field of pharmaceuticals. In particular, it relates to new com...
Cimicifuga species have been used as traditional medicinal herbs to treat inflammation and symptoms ...
Novel esters of non steroidal anti-inflammatory drugs, α-lipoic acid and indol-3-acetic acid with ci...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
Compounds and compositions comprising these compounds, which have immunomodulatory activity and/or a...
The subject invention provides a method for optimal isolation of cimiracemate A for subsequent use a...
A series of lumiracoxib derivatives were designed to explore the influence of isosteric substitution...
Drugs able to inhibit both cyclooxygenases (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) (dual acting...
Inflammation is a complex phenomenon that results as a healing response of organisms to different fa...
The subject invention provides novel and advantageous materials and methods for treating neuroinflam...
A method for treating inflammatory and immune conditions by modulating TNF-a and nitric oxide produc...
A method for treating inflammatory and immune conditions by modulating TNF-[alpha] and nitric oxide ...
Inflammatory mediators are local hormones that act via specific cell-surface receptors in an autocri...
The present invention relates to the field of pharmaceuticals. In particular, it relates to new com...
Cimicifuga species have been used as traditional medicinal herbs to treat inflammation and symptoms ...
Novel esters of non steroidal anti-inflammatory drugs, α-lipoic acid and indol-3-acetic acid with ci...