The effect of inhaled corticosteroids on the risk of diabetes mellitus, prediabetes and glucose regulation in adults with asthma (ICSD Study)

INTRODUCTION: We investigated the risk of long-term inhaled corticosteroids (ICS) on diabetes mellitus (DM), prediabetes, and glucose tolerance in Chinese adult asthmatics in a population-based matched-controlled study. METHODS: A total of 691 asthmatics, aged ≥35 to 74 years, who used ICS regularly for ≥6 months were recruited from four asthma clinics in Hong Kong, excluding those with exacerbation in recent 4 weeks or had taken systemic steroid (SS) in recent 6 months. Each asthmatic was matched 1:1 on age, gender, and body mass index (BMI) with controls from the Hong Kong Cardiovascular Risk Factors Prevalence Study II based on a random population samp…published_or_final_versio