Is aspirin intake associated with early age-related macular degeneration? The Singapore Indian Eye Study

Background/aims: To examine the relationship between aspirin intake and early age-related macular degeneration (AMD) among an Asian population. Methods: A population based cross sectional study of 3207 ethnic Indians aged 40 years or older residing in Singapore. AMD signs were graded from retinal images following the modified Wisconsin grading system. Information on aspirin intake was obtained from a standardised questionnaire. Results: The prevalence of early AMD was 5.6%. Aspirin use was reported by 11.4% of participants. Early AMD signs were present among 10.9% of aspirin users and 4.9% of non-aspirin users (p