Two series of novel compounds designed as hybrids of 1-arylnaphthalene lignans with dihydroisoquinolines or isoquinolines were synthesized and evaluated for their cytotoxicities on human tumor cell lines, such as A549, Hela, PC-3 and KB. Some of the synthetic compounds exhibited their IC 50 values on selected cell lines at μmol/L scale.link_to_subscribed_fulltex
To examine the effect of hydrophobicity on the anticancer activity of 1,4-naphthoquinone derivative...
A new family of molecular hybrids, between cyclolignans related to podophyllic aldehyde and several ...
TAN, Ayse/0000-0003-2692-7923Background: Norcantharimides are known as norcantharidine derivatives a...
Novel compounds designed as hybrids of 1-arylnaphthalene lignans with isoquinoline alkaloids were pr...
International audienceA concise and versatile synthetic strategy for the total synthesis of arylnaph...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
A new series of 2-amino-benzo[de]isoquinoline-1,3-diones was synthesized and fully characterized in ...
Novel antitumoral agents with quinonic structure were synthesized and evaluated for their in vitro c...
A variety of aminoisoquinoline-5,8-quinones bearing α-amino acids moieties were synthesized from 3-m...
International audienceThe cytotoxic activity of a series of 23 new isocombretastatin A derivatives w...
Designed as a new series of molecules that contain the quinoline substructure, several 11H-indolo[3....
Arylnaphthalene lignan lactones have attracted considerable interest because of their anti-tumor and...
A new family of hybrids between cyclolignans related to podophyllic aldehyde, a non-lactonic cycloli...
To examine the effect of hydrophobicity on the anticancer activity of 1,4-naphthoquinone derivative...
A new family of molecular hybrids, between cyclolignans related to podophyllic aldehyde and several ...
TAN, Ayse/0000-0003-2692-7923Background: Norcantharimides are known as norcantharidine derivatives a...
Novel compounds designed as hybrids of 1-arylnaphthalene lignans with isoquinoline alkaloids were pr...
International audienceA concise and versatile synthetic strategy for the total synthesis of arylnaph...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
In this study the syntheses of 11 novel lignans are described. Their cytotoxicities are studied in G...
A new series of 2-amino-benzo[de]isoquinoline-1,3-diones was synthesized and fully characterized in ...
Novel antitumoral agents with quinonic structure were synthesized and evaluated for their in vitro c...
A variety of aminoisoquinoline-5,8-quinones bearing α-amino acids moieties were synthesized from 3-m...
International audienceThe cytotoxic activity of a series of 23 new isocombretastatin A derivatives w...
Designed as a new series of molecules that contain the quinoline substructure, several 11H-indolo[3....
Arylnaphthalene lignan lactones have attracted considerable interest because of their anti-tumor and...
A new family of hybrids between cyclolignans related to podophyllic aldehyde, a non-lactonic cycloli...
To examine the effect of hydrophobicity on the anticancer activity of 1,4-naphthoquinone derivative...
A new family of molecular hybrids, between cyclolignans related to podophyllic aldehyde and several ...
TAN, Ayse/0000-0003-2692-7923Background: Norcantharimides are known as norcantharidine derivatives a...