Association between plasma alkaline phosphatase and C-reactive protein in Hong Kong Chinese
- Woo, J
- Janus, ED
- Ong, KL
- Cheung, RV
- Wong, LYF
- Wat, NMS
- Tam, S
- Cheng, CH
- Lau, CP
- Leung, GM
- Cheung, BMY
- Hing Lam, T
- Lam, KSL
DOIAbstract
Background: Alkaline phosphatase (ALP) is a biomarker for hepatobiliary and skeletal diseases. It is also raised in sepsis. In atherosclerotic plaques, ALP is expressed. Similar to C-reactive protein (CRP), it may be another marker of systemic inflammation. Therefore, we investigated their association in a Hong Kong Chinese population. Methods: Plasma ALP and CRP were measured in 205 subjects (110 men, 95 women; age 55.2±11.6 years) in the Hong Kong Cardiovascular Risk Factor Prevalence Study-2 cohort. Results: The blood levels of ALP and CRP were significantly correlated (r=0.30, p<0.001), which was due to a significant correlation in women (r=0.43, p<0.001). In a multivariate model, CRP level was related to ALP (β=0.18, p=0.008). After ad...
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