Rasta resin-PPh3BnCl and its use in chromatography-free carbonyl cyanosilylation reactions

Rasta resin-PPhnCl, a new heterogeneous polystyrene-based phosphonium salt, has been synthesized and used to catalyze cyanosilylation reactions of aldehydes and ketones. It was found to be more efficient as a catalyst than a similar heterogeneous phosphonium salt anchored onto a polystyrene-based on the Merrifield resin architecture of 2% divinylbenzene cross-linking. In these reactions rasta resin-PPhnCl was separated from the desired reaction product simply by filtration, and it could be reused without significant loss of catalytic activity numerous times. © Georg Thieme Verlag Stuttgart New York.postprin