Activation of nicotinic receptors contributes to acetylcholine induced endothelium-dependent relaxations in rat aorta

The present study was designed to investigate whether or not nicotinic receptors (nAChRs) are involved in endothelium-dependent relaxations evoked by acetylcholine. Male spontaneous hypertensive rats (SHR, 36 weeks) and Wistar Kyoto rats (WKY, 36 weeks & 64 weeks), and both female and male Sprague-Dawley rats (SD, 30 weeks) were used. The aortic rings were incubated with ...link_to_OA_fulltex