Activation of nicotinic receptors contributes to acetylcholine-induced endothelium-dependent relaxations in the aorta of the spontaneous hypertensive rat

Poster SessionThis journal issue is proceedings of ICSM 2010Acetylcholine causes both endothelium-dependent relaxations and contractions in the rat aorta. Both muscarinic (mAChRs) and nicotinic (nAChRs) acetylcholine receptors are expressed in endothelial cells. It is generally accepted that mAChRs [of the M3-subtype] are responsible for both endothelium-dependent relaxations and contractions evoked by acetylcholine. To study the expressions of acetylcholine receptors in rat aorta, PCR primers for different subunits of ...link_to_OA_fulltextThe 14th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM), Hong Kong, China, 18 December 2010. In Journal of the Hong Kong College of Cardiology, 2010, v. 18 n. 2, p. 72, abstract no. P1