1α, 25-Dihydroxyvitamin D3 suppresses differentiation, maturation and activation of dendritic cells from patients with systemic lupus erythematosus

Clinical Research: 2.6 Systemic lupus erythematosus, Sjögren’s and antiphospholipid syndrome – therapiesBACKGROUND: Dendritic cells (DC), professional antigen presenting cells, are believed to play a crucial role in the pathogenesis of systemic lupus erythematosus (SLE). 1a, 25-Dihydroxyvitamin D3 (VitD3), in addition to its effect on bone metabolism, has been increasing recognized to have immunomodulatory effects …link_to_OA_fulltextThe 14th Congress of Asia Pacific League of Associations for Rheumatology, Hong Kong, China, 11-15 July 2010. In International Journal of Rheumatic Diseases, 2010, v. 13 suppl. 1, p. 114, abstract no. 068