Studies on the function of plasmacytoid dendritic cells in healthy and systemic lupus erythematosus

Basic and Translational Research: 1.7. Systemic lupus erythematosus, Sjögren's, systemic vasculitis and antiphospholipid syndrome - pathogenesis and animal modelsBACKGROUND: Dendritic cells (DCs) are professional antigen presenting cells that are capable of inducing either immunity or tolerance. Plasmacytoid DCs (pDCs) have recently been suggested to have a pathoetiologic role in systemic lupus erythematosus (SLE). Our previous studies have found that directly isolated peripheral blood pDCs from SLE has increased capacity to stimulate …link_to_OA_fulltextThe 14th Congress of Asia Pacific League of Associations for Rheumatology, Hong Kong, China, 11-15 July 2010. In International Journal of Rheumatic Diseases, 2010, v. 13 suppl. 1, p. 54, abstract no. 055