Foxp3 mRNA expression on DC subsets in patients of systemic lupus erythematosus

Basic and Translational Research: 1.7. Systemic lupus erythematosus, Sjögren's, systemic vasculitis and antiphospholipid syndrome - pathogenesis and animal modelsBACKGROUND: Dendritic cells (DCs), professional antigen presenting cells which link the innate and adaptive immune systems, play an important role in inducing immunity and tolerance. Systemic lupus erythematosus (SLE), an autoimmune disease with loss of tolerance to self antigens, is suggested to have apoptotic cells as the source of antigens. Foxp3, a transcription factor, is suggested to be …link_to_OA_fulltextThe 14th Congress of Asia Pacific League of Associations for Rheumatology, Hong Kong, China, 11-15 July 2010. In International Journal of Rheumatic Diseases, 2010, v. 13 suppl. 1, p. 55, abstract no. 055