Basic and Translational Research: 1.1 Genomics, genetic basis of disease, HLA/T cell recognitionOBJECTIVE: Previous genome wide association study conducted in a population of European ancestry identified rs4963128, a KIAA1542 SNP 23kb telomeric to IRF7, in strong association with SLE. This study was undertaken to investigate whether genetic polymorphism within IRF7 is a risk factor for the development of SLE. METHODS: A total of 5024 individuals from multiple ethnic groups …link_to_OA_fulltextThe 14th Congress of Asia Pacific League of Associations for Rheumatology, Hong Kong, China, 11-15 July 2010. In International Journal of Rheumatic Diseases, 2010, v. 13 suppl. 1, p. 9, abstract no. 069
A classic T-cell phenotype in systemic lupus erythematosus (SLE) is the downregulation and replaceme...
Systemic Lupus Erythematous (SLE) is a chronic, multisystem autoimmune disease that is characterized...
SLE is a complicated autoimmune disease with a strong genetic basis. Owing to the successful applica...
Objective. A previous genome-wide association study conducted in a population of European ancestry i...
A previous genome-wide association study conducted in a population of European ancestry identified r...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic architecture. We...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the ...
Interferon regulatory factor 7 (IRF7) has an essential role in the production of type I interferon. ...
Systemic lupus erythematosus (SLE) is characterized as an autoimmune disorder with unclear etiology....
Epidemiological studies suggest a strong contribution of genetic factors in the pathogenesis of syst...
The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this oc...
International audienceOBJECTIVE: Interferon regulatory factor 5 (IRF-5) is a transcription factor in...
A classic T-cell phenotype in systemic lupus erythematosus (SLE) is the downregulation and replaceme...
Systemic Lupus Erythematous (SLE) is a chronic, multisystem autoimmune disease that is characterized...
SLE is a complicated autoimmune disease with a strong genetic basis. Owing to the successful applica...
Objective. A previous genome-wide association study conducted in a population of European ancestry i...
A previous genome-wide association study conducted in a population of European ancestry identified r...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by t...
Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic architecture. We...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the ...
Interferon regulatory factor 7 (IRF7) has an essential role in the production of type I interferon. ...
Systemic lupus erythematosus (SLE) is characterized as an autoimmune disorder with unclear etiology....
Epidemiological studies suggest a strong contribution of genetic factors in the pathogenesis of syst...
The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this oc...
International audienceOBJECTIVE: Interferon regulatory factor 5 (IRF-5) is a transcription factor in...
A classic T-cell phenotype in systemic lupus erythematosus (SLE) is the downregulation and replaceme...
Systemic Lupus Erythematous (SLE) is a chronic, multisystem autoimmune disease that is characterized...
SLE is a complicated autoimmune disease with a strong genetic basis. Owing to the successful applica...