Background and aim: Although surgical procedures are the first front treatments for liver cancer, tumor recurrence or metastasis remains to be the major problem, which significantly affects the long-term disease-free survival. Therefore, development of novel adjuvant therapies targeting for liver cancer growth, recurrence/metastasis will be essential. Angiopoietin-like protein 4 (ANGPLT-4) has been recently demonstrated to be able to inhibit tumor invasiveness by modification of cytoskeleton organization. In the present study, we aim to investigate the effect of ANGPLT-4 on liver cancer growth and metastasis in an orthotopic nude mice liver cancer model with metastatic potentials. Materials and methods: The orthotopic liver tumor nude mi...
The epithelial-mesenchymal transition (EMT) serves as a pivotal mechanism in the progression of met...
Recently, fat-derived hormone adiponectin has been demonstrated to be able to suppress angiogenesis ...
There is strong evidence that the angiopoietin family is involved in the regulation of tumour progre...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular ne...
Resistance to anti-angiogenic therapy is a major challenge in the treatment of colorectal cancer liv...
Metastatic liver cancer has a very poor prognosis and lacks effective therapy. Anti-angiogenic thera...
Metastasis, the spread of cancer cells to distant tissues and/or organs, accounts for more than 90% ...
Metastasis, the spread of cancer cells to distant tissues and/or organs, accounts for more than 90% ...
Cancer is a leading cause of death worldwide. Tumor cells exploit various signaling molecules to pro...
Introduction: Metastatic progression in triple-negative breast cancer (TNBC) patients occurs primari...
The epithelial-mesenchymal transition (EMT) serves as a pivotal mechanism in the progression of met...
Recently, fat-derived hormone adiponectin has been demonstrated to be able to suppress angiogenesis ...
There is strong evidence that the angiopoietin family is involved in the regulation of tumour progre...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietin-like 4 (ANGPTL4), a secreted protein of the angiopoietin-like family, is induced by hyp...
Angiopoietins (Ang) are involved in the remodeling, maturation, and stabilization of the vascular ne...
Resistance to anti-angiogenic therapy is a major challenge in the treatment of colorectal cancer liv...
Metastatic liver cancer has a very poor prognosis and lacks effective therapy. Anti-angiogenic thera...
Metastasis, the spread of cancer cells to distant tissues and/or organs, accounts for more than 90% ...
Metastasis, the spread of cancer cells to distant tissues and/or organs, accounts for more than 90% ...
Cancer is a leading cause of death worldwide. Tumor cells exploit various signaling molecules to pro...
Introduction: Metastatic progression in triple-negative breast cancer (TNBC) patients occurs primari...
The epithelial-mesenchymal transition (EMT) serves as a pivotal mechanism in the progression of met...
Recently, fat-derived hormone adiponectin has been demonstrated to be able to suppress angiogenesis ...
There is strong evidence that the angiopoietin family is involved in the regulation of tumour progre...