We describe a universal sample multiplexing method for single-cell RNA sequencing in which fixed cells are chemically labeled by attaching identifying DNA oligonucleotides to cellular proteins. Analysis of a 96-plex perturbation experiment revealed changes in cell population structure and transcriptional states that cannot be discerned from bulk measurements, establishing an efficient method for surveying cell populations from large experiments or clinical samples with the depth and resolution of single-cell RNA sequencing
For the past several decades, due to technical limitations, the field of transcriptomics has focused...
BackgroundRecently, measurement of RNA at single cell resolution has yielded surprising insights. Me...
Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular heterogen...
We describe a universal sample multiplexing method for single-cell RNA sequencing in which fixed cel...
We describe a universal sample multiplexing method for single-cell RNA sequencing in which fixed cel...
This directory contains sequencing data in fastq format for three scRNA-seq experiments found in Geh...
Multicellular organisms rely on diverse cell types to carry out the multitude of tasks necessaryfor ...
Advances in single-cell analysis technologies are providing novel insights into phenotypic and funct...
Cellular biology has traditionally relied upon simple, low-dimensional single-cell measurements (e.g...
Cellular biology has traditionally relied upon simple, low-dimensional single-cell measurements (e.g...
The transcriptome of a cell contains a wealth of information about the cell’s current state and its ...
abstract: The understanding of normal human physiology and disease pathogenesis shows great promise ...
Despite being a relatively recent technological development, single-cell transcriptional analysis th...
Single cell RNA sequencing methods have been increasingly used to understand cellular heterogeneity....
Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phen...
For the past several decades, due to technical limitations, the field of transcriptomics has focused...
BackgroundRecently, measurement of RNA at single cell resolution has yielded surprising insights. Me...
Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular heterogen...
We describe a universal sample multiplexing method for single-cell RNA sequencing in which fixed cel...
We describe a universal sample multiplexing method for single-cell RNA sequencing in which fixed cel...
This directory contains sequencing data in fastq format for three scRNA-seq experiments found in Geh...
Multicellular organisms rely on diverse cell types to carry out the multitude of tasks necessaryfor ...
Advances in single-cell analysis technologies are providing novel insights into phenotypic and funct...
Cellular biology has traditionally relied upon simple, low-dimensional single-cell measurements (e.g...
Cellular biology has traditionally relied upon simple, low-dimensional single-cell measurements (e.g...
The transcriptome of a cell contains a wealth of information about the cell’s current state and its ...
abstract: The understanding of normal human physiology and disease pathogenesis shows great promise ...
Despite being a relatively recent technological development, single-cell transcriptional analysis th...
Single cell RNA sequencing methods have been increasingly used to understand cellular heterogeneity....
Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phen...
For the past several decades, due to technical limitations, the field of transcriptomics has focused...
BackgroundRecently, measurement of RNA at single cell resolution has yielded surprising insights. Me...
Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular heterogen...