Add to ORKGWe report a divergent and modular protocol for the preparation of acyclic molecular frameworks containing newly created quaternary carbon stereocenters. Central to this approach is a sequence composed of a (1) regioselective and -retentive preparation of allyloxycarbonyl-trapped fully substituted stereodefined amide enolates and of a (2) enantioselective palladium-catalyzed decarboxylative allylic alkylation reaction using a novel bisphosphine ligand
Notwithstanding advances in modern chemical methods, the selective installation of sterically encumb...
A catalytic enantioselective method for the synthesis of α-quaternary Mannich-type products is repor...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
The palladium-catalyzed decarboxylative allylic alkylation of enol carbonates derived from lactams a...
α-Quaternary ketones are accessed through novel enantioselective alkylations of allyl and propargyl ...
All-carbon quaternary stereocenters have posed significant challenges in the synthesis of complex na...
Enantioselective catalytic allylic alkylation for the synthesis of 2-alkyl-2-allylcycloalkanones and...
The ever-present demand for drugs with better efficacy and fewer side effects continually motivates ...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
The enantioselective synthesis of nitrogen-containing heterocycles (N-heterocycles) represents a sub...
Highly congested vicinal stereocenters comprised of tertiary and all-carbon quaternary centers were ...
Stereochemical alchemy! Racemic allyl β-ketoesters allow the regiocontrolled formation of enolates, ...
The catalytic enantioselective preparation of all-carbon quaternary stereocenters within rings via a...
Notwithstanding advances in modern chemical methods, the selective installation of sterically encumb...
A catalytic enantioselective method for the synthesis of α-quaternary Mannich-type products is repor...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks conta...
The palladium-catalyzed decarboxylative allylic alkylation of enol carbonates derived from lactams a...
α-Quaternary ketones are accessed through novel enantioselective alkylations of allyl and propargyl ...
All-carbon quaternary stereocenters have posed significant challenges in the synthesis of complex na...
Enantioselective catalytic allylic alkylation for the synthesis of 2-alkyl-2-allylcycloalkanones and...
The ever-present demand for drugs with better efficacy and fewer side effects continually motivates ...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
The enantioselective synthesis of nitrogen-containing heterocycles (N-heterocycles) represents a sub...
Highly congested vicinal stereocenters comprised of tertiary and all-carbon quaternary centers were ...
Stereochemical alchemy! Racemic allyl β-ketoesters allow the regiocontrolled formation of enolates, ...
The catalytic enantioselective preparation of all-carbon quaternary stereocenters within rings via a...
Notwithstanding advances in modern chemical methods, the selective installation of sterically encumb...
A catalytic enantioselective method for the synthesis of α-quaternary Mannich-type products is repor...
A new general three-stage strategy to access polycyclic ring systems bearing all-carbon quaternary c...