A field study on EROD activity and quantitative hepatocytological changes in an immature demersal fish

Demersal fish, Solea ovata, were sampled from a reference site and a site where highly contaminated sediment is dumped. Sexually immature fish from the contaminated site exhibited significantly higher EROD activity compared with counterparts sampled from the reference site. No significant difference in EROD activity could be found for sexually mature males and females between sites. The relationship between EROD activity and quantitative changes in hepatic lipofuscin/ceroid, as well as peroxisome, was investigated for immature S. ovata. A significant correlation was found between EROD activity and volume density of lipofuscin/ceroid in fish hepatocyte (r=0.750; P