The neural crest is a uniquely vertebrate cell type and has been well studied in a number of model systems. Zebrafish, Xenopus and chick embryos largely show consistent requirements for specific genes in early steps of neural crest development. By contrast, knockouts of homologous genes in the mouse often do not exhibit comparable early neural crest phenotypes. In this Spotlight article, we discuss these species-specific differences, suggest possible explanations for the divergent phenotypes in mouse and urge the community to consider these issues and the need for further research in complementary systems
The neural crest (NC) is a stem cell-like embryonic population that is essential for generating and ...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...
The neural crest is a uniquely vertebrate cell type and has been well studied in a number of model s...
AbstractThe neural crest is a multipotent and migratory cell type that forms transiently in the deve...
The neural crest is a multipotent and migratory cell type that forms transiently in the developing v...
Vertebrate neural crest cells are multipotent and differentiate into structures that include cartil...
The neural crest is a transient population of multipotent precursor cells named for its site of orig...
The neural crest is a multipotent and highly migratory cell type that contributes to many of the def...
The neural crest is an excellent model system for the study of cell type diversification during embr...
The availability of naturally occurring and engineered mutations in mice which affect the neural cre...
Neural crest cells are a fascinating embryonic cell type, unique to vertebrates, which arise within ...
Neural crest cells are a fascinating embryonic cell type, unique to vertebrates, which arise within ...
The availability of naturally occurring and engineered mutations in mice which affect the neural cre...
AbstractIn the vertebrate embryo, the neural crest forms transiently in the dorsal neural primordium...
The neural crest (NC) is a stem cell-like embryonic population that is essential for generating and ...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...
The neural crest is a uniquely vertebrate cell type and has been well studied in a number of model s...
AbstractThe neural crest is a multipotent and migratory cell type that forms transiently in the deve...
The neural crest is a multipotent and migratory cell type that forms transiently in the developing v...
Vertebrate neural crest cells are multipotent and differentiate into structures that include cartil...
The neural crest is a transient population of multipotent precursor cells named for its site of orig...
The neural crest is a multipotent and highly migratory cell type that contributes to many of the def...
The neural crest is an excellent model system for the study of cell type diversification during embr...
The availability of naturally occurring and engineered mutations in mice which affect the neural cre...
Neural crest cells are a fascinating embryonic cell type, unique to vertebrates, which arise within ...
Neural crest cells are a fascinating embryonic cell type, unique to vertebrates, which arise within ...
The availability of naturally occurring and engineered mutations in mice which affect the neural cre...
AbstractIn the vertebrate embryo, the neural crest forms transiently in the dorsal neural primordium...
The neural crest (NC) is a stem cell-like embryonic population that is essential for generating and ...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...
From the initial discovery of the neural crest over 150 years ago to the seminal studies of Le Douar...