ArticleVitamin D3 has transcriptome- and genome-wide effects and activates, via the binding of its metabolite 1α,25-dihydroxyvitamin D3 to the transcription factor vitamin D receptor (VDR), several hundred target genes. Using samples from a 5-month vitamin D3 intervention study (VitDmet), we recently reported that the expression of 12 VDR target genes in peripheral blood mononuclear cells (PBMCs) as well as 12 biochemical and clinical parameters of the study participants are significantly triggered by vitamin D3. In this study, we performed a more focused selection of further 12 VDR target genes and demonstrated that changes of their mRNA expression in PBMCs of VitDmet subjects significantly correlate with alterations of 25-hydroxyvitamin D...
Vitamin D3 has, via its metabolite 1,25-dihydroxyvitaminD3 (1,25(OH)2D3), a high affinity to the tra...
In addition to its canonical functions, vitamin D has been proposed to be an important mediator of t...
Although there have been numerous observations of vitamin D deficiency and its links to chronic dise...
<div><p>Vitamin D<sub>3</sub> has transcriptome- and genome-wide effects and activates, via the bind...
Vitamin D3 has transcriptome- and genome-wide effects and activates, via the binding of its metaboli...
The vitamin D3 metabolite 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] is the exclusive high-affinity lig...
ArticleVitamin D3 is one of the few natural compounds that has, via its metabolite 1α,25-dihydroxyvi...
The molecular basis of vitamin D signaling implies that the metabolite 1α,25-dihydroxyvitamin D3 (1,...
Vitamin D is hydroxylated in the liver and kidneys to its active form, which can bind to the vitamin...
Vitamin D deficiency has been associated with an increased risk of developing a number of diseases. ...
Vitamin D deficiency has been associated with an increased risk of developing a number of diseases. ...
<div><p>Vitamin D deficiency has been associated with an increased risk of developing a number of di...
General knowledge of the role of vitamin D3 in human physiology has been shaped by its discovery as...
The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologi...
The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydr...
Vitamin D3 has, via its metabolite 1,25-dihydroxyvitaminD3 (1,25(OH)2D3), a high affinity to the tra...
In addition to its canonical functions, vitamin D has been proposed to be an important mediator of t...
Although there have been numerous observations of vitamin D deficiency and its links to chronic dise...
<div><p>Vitamin D<sub>3</sub> has transcriptome- and genome-wide effects and activates, via the bind...
Vitamin D3 has transcriptome- and genome-wide effects and activates, via the binding of its metaboli...
The vitamin D3 metabolite 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] is the exclusive high-affinity lig...
ArticleVitamin D3 is one of the few natural compounds that has, via its metabolite 1α,25-dihydroxyvi...
The molecular basis of vitamin D signaling implies that the metabolite 1α,25-dihydroxyvitamin D3 (1,...
Vitamin D is hydroxylated in the liver and kidneys to its active form, which can bind to the vitamin...
Vitamin D deficiency has been associated with an increased risk of developing a number of diseases. ...
Vitamin D deficiency has been associated with an increased risk of developing a number of diseases. ...
<div><p>Vitamin D deficiency has been associated with an increased risk of developing a number of di...
General knowledge of the role of vitamin D3 in human physiology has been shaped by its discovery as...
The transcription factor vitamin D receptor (VDR) is the high affinity nuclear target of the biologi...
The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydr...
Vitamin D3 has, via its metabolite 1,25-dihydroxyvitaminD3 (1,25(OH)2D3), a high affinity to the tra...
In addition to its canonical functions, vitamin D has been proposed to be an important mediator of t...
Although there have been numerous observations of vitamin D deficiency and its links to chronic dise...