Background. Age-related skewing of X-chromosome inactivation leading to glucose-6-phosphate dehydrogenase (G6PD) deficiency in elderly women in a population with prevalent G6PD gene mutations was investigated. Methods. G6PD activity was measured biochemically. G6PD mutations were detected by polymerase chain reaction (PCR) and allele-specific extension, and analyzed by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry and Sequenom MassARRAY. X-chromosome inactivation was quantified by semiquantitative PCR for the HUMARA gene, before and after HpaII digestion. Results. In 173 women (median age: 90 years; range, 80-107 years), 18 heterozygotes for G6PD mutations were identified. Three heterozygotes were ...
To determine whether during hematopoietic stem cell transplantation (HSCT), X-chromosome inactivatio...
The pathophysiology, diagnosis, and medication-use implications of glucose-6-phosphate dehydrogenase...
<p>Similar to the thalassaemia syndromes, glucose-6-phosphate dehydrogenase (G6PD) deficiency is hig...
Background. Age-related skewing of X-chromosome inactivation leading to glucose-6-phosphate dehydrog...
Glucose-6-phosphate dehydrogenase is an essential enzyme to cell growth. Its deficiency of enzyme pl...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked disorder, is usually observed in he...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect, being pr...
Glucose 6 Phosphate Dehydrogenase (G6PD) is one of the rate-limiting enzymes in hexose monophosphate...
Deficiency of glucose-6-phosphate dehydrogenase (G6PD) is the commonest enzyme deficiency in humans ...
Recent studies suggest that X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency entails a p...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary condition caused by mutations on...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited disorder common in Sardinia. In ...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common X-linked human enzyme defect of red ...
Glucose-6-phosphate dehydrogenase (G6PD) Deficiency is the most prevalent enzymopathy in mankind. It...
Glucose-6-phosphate dehydrogenase (G6PD) Deficiency is the most prevalent enzymopathy in mankind. It...
To determine whether during hematopoietic stem cell transplantation (HSCT), X-chromosome inactivatio...
The pathophysiology, diagnosis, and medication-use implications of glucose-6-phosphate dehydrogenase...
<p>Similar to the thalassaemia syndromes, glucose-6-phosphate dehydrogenase (G6PD) deficiency is hig...
Background. Age-related skewing of X-chromosome inactivation leading to glucose-6-phosphate dehydrog...
Glucose-6-phosphate dehydrogenase is an essential enzyme to cell growth. Its deficiency of enzyme pl...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked disorder, is usually observed in he...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect, being pr...
Glucose 6 Phosphate Dehydrogenase (G6PD) is one of the rate-limiting enzymes in hexose monophosphate...
Deficiency of glucose-6-phosphate dehydrogenase (G6PD) is the commonest enzyme deficiency in humans ...
Recent studies suggest that X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency entails a p...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary condition caused by mutations on...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited disorder common in Sardinia. In ...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common X-linked human enzyme defect of red ...
Glucose-6-phosphate dehydrogenase (G6PD) Deficiency is the most prevalent enzymopathy in mankind. It...
Glucose-6-phosphate dehydrogenase (G6PD) Deficiency is the most prevalent enzymopathy in mankind. It...
To determine whether during hematopoietic stem cell transplantation (HSCT), X-chromosome inactivatio...
The pathophysiology, diagnosis, and medication-use implications of glucose-6-phosphate dehydrogenase...
<p>Similar to the thalassaemia syndromes, glucose-6-phosphate dehydrogenase (G6PD) deficiency is hig...