Adjuvant chemotherapy alongside radiotherapy is one of the effective therapies in nasopharyngeal carcinoma (NPC) treatment. However, the appearance of drug resistance is a major obstacle for anti-cancer chemotherapy and often causes failure of the chemotherapy. In this study, a drug-resistant gene annexin I (ANX-I) was identified by comparing differentially expressed proteins between a cisplatin (CDDP)-resistant NPC cell line CNE2-CDDP and parental CNE2 cells using 2-DE. When ANX-I was transfected into CNE2 cells, the CDDP resistance of CNE2 cells was dramatically increased. The drug-resistant ability of ANX-I was demonstrated by both in vitro and in vivo assays. The association of ANX-I expression with clinical features was also investigat...
BACKGROUND: Annexin A1 (AnxA1) has been well-known as a glucocorticoid-regulated anti-inflammatory p...
Annexin A1 (ANXA1) is an anti-inflammatory protein reported to play a role in cell proliferation and...
Annexin A1 (ANXA1) has been reported to promote tumor growth and resistance to chemotherapy drugs in...
Abstract Nasopharyngeal carcinoma (NPC) is a head and neck cancer with poor clinical outcomes and in...
Abstract Background Development of resistance to therapy continues to be a serious clinical problem ...
Ovarian cancer patients treated with cisplatin-based chemotherapy often develop acquired cisplatin r...
Ovarian cancer patients treated with cisplatin-based chemotherapy often develop acquired cisplatin r...
In this study, we have characterized the role of annexin A1 (ANXA1) in the acquisition and maintenan...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
BACKGROUND: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Annexin A2 (ANXA2) orchestrates multiple biologic processes and clinical associations, especially in...
Abstract Background Chemotherapy is one of major therapeutic regimens for neuroblastoma (NB) in chil...
BACKGROUND: Annexin A1 (AnxA1) has been well-known as a glucocorticoid-regulated anti-inflammatory p...
Annexin A1 (ANXA1) is an anti-inflammatory protein reported to play a role in cell proliferation and...
Annexin A1 (ANXA1) has been reported to promote tumor growth and resistance to chemotherapy drugs in...
Abstract Nasopharyngeal carcinoma (NPC) is a head and neck cancer with poor clinical outcomes and in...
Abstract Background Development of resistance to therapy continues to be a serious clinical problem ...
Ovarian cancer patients treated with cisplatin-based chemotherapy often develop acquired cisplatin r...
Ovarian cancer patients treated with cisplatin-based chemotherapy often develop acquired cisplatin r...
In this study, we have characterized the role of annexin A1 (ANXA1) in the acquisition and maintenan...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Background: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
BACKGROUND: Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis f...
Annexin A2 (ANXA2) orchestrates multiple biologic processes and clinical associations, especially in...
Abstract Background Chemotherapy is one of major therapeutic regimens for neuroblastoma (NB) in chil...
BACKGROUND: Annexin A1 (AnxA1) has been well-known as a glucocorticoid-regulated anti-inflammatory p...
Annexin A1 (ANXA1) is an anti-inflammatory protein reported to play a role in cell proliferation and...
Annexin A1 (ANXA1) has been reported to promote tumor growth and resistance to chemotherapy drugs in...