Add to ORKGThe levels and types of immune responses are determined dependent on the extent of pathogen invasion, reactions to antigens mediated by macrophage-dendritic cells, T cells and antibodies. Recently, accumulating evidence suggests that B cells also play an important role in the regulation of immune responses. Here we have made a review to present a role of B cells in determining the level of immune responses and discussed about the clinical significance of B cell-targeted therapy in patients with autoimmune diseases. Type 1 diabetes is a T cell-mediated autoimmune disease characterized by the destruction of insulin-producing pancreatic A3 cells. We and other groups have elucidated that B cells play a critical role in the development of insuli...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
Although type 1 diabetes is thought to be an organ-specific autoimmune disease, mediated by effectiv...
B cells are major effector cells in autoimmunity through antibody production, T cell help and pro-in...
B cells are recognized as main actors in the autoimmune process. Autoreactive B cells can arise in t...
B cell-depletion therapy, particularly using anti-CD20 treatment, has provided proof of concept that...
Copyright © 2012 Christiane S. Hampe.is is an open access article distributed under theCreativeCommo...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Reasons for targeting B cells in autoimmune disease date back to the discovery of autoantibodies ove...
Success with B cell depletion using rituximab has proven the concept that B lineage cells represent ...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Interleukin (IL)-10-secreting regulatory Bcells(B10) are acknowledged to play important roles in bal...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Autoantibodies are a common feature of all autoimmune diseases. The molecules against which autoanti...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
Although type 1 diabetes is thought to be an organ-specific autoimmune disease, mediated by effectiv...
B cells are major effector cells in autoimmunity through antibody production, T cell help and pro-in...
B cells are recognized as main actors in the autoimmune process. Autoreactive B cells can arise in t...
B cell-depletion therapy, particularly using anti-CD20 treatment, has provided proof of concept that...
Copyright © 2012 Christiane S. Hampe.is is an open access article distributed under theCreativeCommo...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Reasons for targeting B cells in autoimmune disease date back to the discovery of autoantibodies ove...
Success with B cell depletion using rituximab has proven the concept that B lineage cells represent ...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Interleukin (IL)-10-secreting regulatory Bcells(B10) are acknowledged to play important roles in bal...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
B cells have a vitally important function to produce antibodies which are directly pathogenic in som...
Autoantibodies are a common feature of all autoimmune diseases. The molecules against which autoanti...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
B cells have emerged as effective targets for therapeutic intervention in autoimmunities in which th...
Although type 1 diabetes is thought to be an organ-specific autoimmune disease, mediated by effectiv...