<p>Transplantation of a functional engineered skeletal muscle substitute is a promising therapeutic option to repair irreversible muscle damage, and, on the other hand, functional muscle tissue constructs can serve as in vitro 3D tissue models that complement the conventional 2D cell cultures and animal models to advance our limited understanding of intrinsic myogenesis and muscle regeneration process. However, the engineering of skeletal muscle constructs with comparable contractile function to the native muscle is hampered by the lack of 1) effective and reproducible methods to form relatively large muscle constructs composed of viable, dense, aligned and matured myofibers, and 2) beneficial microenvironmental cues as well as physiologica...
<p>Skeletal muscle is a scalable actuator system used throughout nature from the millimeter to meter...
Tissue engineered skeletal muscle has great utility in experimental studies of physiology, clinical ...
Kroehne V, Heschel I, Schuegner F, Lasrich D, Bartsch JW, Jockusch H. Use of a novel collagen matrix...
The growing deficit in suitable tissues for patients awaiting organ transplants demonstrates the cli...
Skeletal muscle is a complex tissue with a capacity to regenerate upon injury. However, when skeleta...
Skeletal muscle related diseases cause loss and weakness in the muscle and affect the quality of lif...
Myofibers, the basic structural elements of skeletal muscle tissue, are formed and regenerated after...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2019Cat...
Engineered muscle tissues can be used for several different purposes, which include the production o...
Many congenital skeletal muscle disorders including muscular dystrophies are caused by genetic mutat...
Tissue engineered skeletal muscle has great potential to successfully treat volumetric muscle loss (...
[eng] The skeletal muscle is the largest tissue of the human body. Its main function is to generate ...
Skeletal muscle tissue is characterized by high metabolic requirements, defined structure and high r...
The purpose of this article is to give a concise review of the current state of the art in tissue en...
Skeletal muscle tissue damage costs the US government hundreds of billions of dollars annually. Mean...
<p>Skeletal muscle is a scalable actuator system used throughout nature from the millimeter to meter...
Tissue engineered skeletal muscle has great utility in experimental studies of physiology, clinical ...
Kroehne V, Heschel I, Schuegner F, Lasrich D, Bartsch JW, Jockusch H. Use of a novel collagen matrix...
The growing deficit in suitable tissues for patients awaiting organ transplants demonstrates the cli...
Skeletal muscle is a complex tissue with a capacity to regenerate upon injury. However, when skeleta...
Skeletal muscle related diseases cause loss and weakness in the muscle and affect the quality of lif...
Myofibers, the basic structural elements of skeletal muscle tissue, are formed and regenerated after...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2019Cat...
Engineered muscle tissues can be used for several different purposes, which include the production o...
Many congenital skeletal muscle disorders including muscular dystrophies are caused by genetic mutat...
Tissue engineered skeletal muscle has great potential to successfully treat volumetric muscle loss (...
[eng] The skeletal muscle is the largest tissue of the human body. Its main function is to generate ...
Skeletal muscle tissue is characterized by high metabolic requirements, defined structure and high r...
The purpose of this article is to give a concise review of the current state of the art in tissue en...
Skeletal muscle tissue damage costs the US government hundreds of billions of dollars annually. Mean...
<p>Skeletal muscle is a scalable actuator system used throughout nature from the millimeter to meter...
Tissue engineered skeletal muscle has great utility in experimental studies of physiology, clinical ...
Kroehne V, Heschel I, Schuegner F, Lasrich D, Bartsch JW, Jockusch H. Use of a novel collagen matrix...