Add to ORKG<p>The specification of a single axon and multiple dendrites is the first observable event during neuronal morphogenesis and such structural specialization underlies neural connectivity and nervous system function. Numerous intracellular signaling components that are required for axon specification have been described but how such signaling paradigms are initiated by extracellular factor(s) within the embryonic milieu is poorly understood. Here, I describe how transforming growth factor-β (TGF-β), an embryonic morphogen that directs structural plasticity and growth in various cell types, initiates signaling pathways both in vivo and in vitro to fate naïve neurites into axons. Using conditional knockout strategies, I found that c...
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (...
In the developing nervous system, the regulation of axonal growth and guidance is the responsibility...
AbstractTransforming growth factor-β (TGF-β) is a multifunctional polypeptide which plays a crucial ...
SummaryIn the mammalian brain, the specification of a single axon and multiple dendrites occurs earl...
In the mammalian brain, the specification of a single axon and multiple dendrites occurs early in th...
In the mammalian brain, the specification of a single axon and multiple dendrites occurs early in th...
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (...
Axon growth is a highly regulated process that requires stimulating signals from extracellular facto...
Axon growth is a highly regulated process that requires stimulating signals from extracellular facto...
The nervous system is developed under the regulation of growth and guidance cues. This process is hi...
Intercellular signaling is vital for the coordinated development of multicellular organisms. This is...
Abstract. Transforming growth factor beta (TGF-β) signaling has diverse and complex roles in various...
The establishment of correct neural circuitry in the nervous system requires the interplay, integrat...
The establishment of correct neural circuitry in the nervous system requires the interplay, integrat...
The ability of neurons to form a single axon and multiple dendrites underlies the directional flow o...
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (...
In the developing nervous system, the regulation of axonal growth and guidance is the responsibility...
AbstractTransforming growth factor-β (TGF-β) is a multifunctional polypeptide which plays a crucial ...
SummaryIn the mammalian brain, the specification of a single axon and multiple dendrites occurs earl...
In the mammalian brain, the specification of a single axon and multiple dendrites occurs early in th...
In the mammalian brain, the specification of a single axon and multiple dendrites occurs early in th...
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (...
Axon growth is a highly regulated process that requires stimulating signals from extracellular facto...
Axon growth is a highly regulated process that requires stimulating signals from extracellular facto...
The nervous system is developed under the regulation of growth and guidance cues. This process is hi...
Intercellular signaling is vital for the coordinated development of multicellular organisms. This is...
Abstract. Transforming growth factor beta (TGF-β) signaling has diverse and complex roles in various...
The establishment of correct neural circuitry in the nervous system requires the interplay, integrat...
The establishment of correct neural circuitry in the nervous system requires the interplay, integrat...
The ability of neurons to form a single axon and multiple dendrites underlies the directional flow o...
How does a newborn neuron initiate and elaborate an axon? Using cutting-edge approaches, Yi et al. (...
In the developing nervous system, the regulation of axonal growth and guidance is the responsibility...
AbstractTransforming growth factor-β (TGF-β) is a multifunctional polypeptide which plays a crucial ...