Effect of smoking cessation on non-surgical periodontal therapy: results after 24 months

Aim: the aim of this 24-month prospective study was to assess the effect of smoking cessation on non-surgical periodontal therapy (NSPT) in adult subjects with chronic periodontitis.Materials and Methods: Relative to a previous 12-month follow-up study, recruitment and follow-up period were extended, resulting in 116 eligible among the 286 screened subjects. They received NSPT and concurrent smoking cessation interventions. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, performed full-mouth periodontal examination in six sites per tooth at baseline, 3, 12 and 24 months of follow-up. Expired air carbon monoxide concentration measurements and interviews were performed to gather demographic and behavioural information.Results: From the 116 enrolled subjects, 61 remained up to 24 months of follow-up. of these, 18 quit smoking (Q), 32 continued smoking (NQ) and 11 oscillated (O) at 24 months of follow-up. Thereby, Q showed significantly higher mean CAL gain in diseased sites and higher reduction in the proportion of sites with CAL >= 3 mm, when compared to NQ. in addition, Q presented significantly higher mean probing depth reduction relative to NQ(p <= 0.05).Conclusion: Smoking cessation promoted additional benefits on NSPT in chronic periodontitis subjects.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ São Paulo, Sch Dent, Div Periodont, Dept Stomatol, BR-05508000 São Paulo, BrazilAarhus Univ, Dept Clin Epidemiol, Aarhus, DenmarkUniv São Paulo, Univ Hosp, Dept Pediat, BR-05508000 São Paulo, BrazilFAPESP: 07/54494-3Web of Scienc