Paracoccidioidal Infection in HIV Patients at an Endemic Area of Paracoccidioidomycosis in Brazil

The association between paracoccidioidomycosis (PCM) and AIDS is relatively rare in contrast to the higher incidence of other systemic mycosis. the explanation may be that AIDS is still predominantly an urban disease, and the PCM is endemic in Latin American rural areas. the aim of this study was to detect the prevalence of Paracoccidioides brasiliensis infection in HIV-positive patients at an endemic area of paracoccidioidomycosis in Brazil. Skin test with purified 43 kD glycoprotein (gp43) was performed in 90 HIV/AIDS patients. the prevalence found was 12.2% and it may be even greater, considering that HIV/AIDS patients may not respond to the intradermal test, which depends on cellular immunity for its positivity.Departamento de Ciencia e Tecnologia do Ministerio da Saude (DECIT MS/Brazil- UNESCO)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Fed Mato Grosso do Sul, BR-79010070 Campo Grande, MS, BrazilUniv Anhanguera Uniderp, BR-79003010 Campo Grande, MS, BrazilUniv Fed Mato Grosso do Sul, BR-79041080 Campo Grande, MS, BrazilUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, BR-04023062 São Paulo, BrazilWeb of Scienc