Mandibular exercises improve mandibular advancement device therapy for obstructive sleep apnea

Temporomandibular disorder (TMD) has been the most common contraindication for mandibular advancement device (MAD) as a treatment for obstructive sleep apnea syndrome (OSAS). Exercising the mandible is a recommended form of therapy for TMD.To assess the efficacy of mandibular exercises in the control of pain, changes of quality of life and to assess the impact of MAD compliance in OSAS patients with previously diagnosed TMD.A blind, randomized, and controlled trial was used to evaluate 29 OSAS patients with TMDs were divided in two groups: the exercise support therapy (ST) and placebo therapy (PT), who were evaluated prior to and 120 days after MAD treatment. Treatment outcomes were measured using the Fletcher and Luckett sleep questionnaire, Epworth sleepiness scale, SF-36 inventory of quality of life, polysomnography, diary of MAD usage, and the research diagnostic criteria for TMD.ST group showed significant improvement in their sleep quality and life quality when compared to the PT group (p < 0.05). Higher number of patients with persistent pain was observed in the PT group (p = 0.01). There was a reduction of pain intensity in the ST group, but not in the PT group (p < 0.05). Higher MAD compliance was observed in the ST group (p < 0.05).Mandibular exercises enable patients with TMD to use MAD; exercises were found to be effective in reducing pain and increasing MAD compliance and produced a significant improvement in the quality of life and quality of sleep.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Associacao Fundo de Incentivo a Psicofarmacologia (AFIP)Univ Fed Parana, Dept Dent, BR-80040270 Curitiba, Parana, BrazilUniversidade Federal de São Paulo, Psichobiol Dept, Sleep Med & Biol Discipline, St Paul, SP, BrazilUniv British Columbia, Dept Oral Hlth Sci, Vancouver, BC V5Z 1M9, CanadaUniversidade Federal de São Paulo, Psichobiol Dept, Sleep Med & Biol Discipline, St Paul, SP, BrazilFAPESP: 2006/04488-4Web of Scienc