Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile

Background: the effects of chronic aerobic exercise upon lipid profile has been previously demonstrated, but few studies showed this effect under resistance exercise conditions.Objective: the aim of this study was to examine the effects of different resistance exercise loads on blood lipids.Methods: Thirty healthy, untrained male volunteers were allocated randomly into four groups based at different percentages of one repetition maximum (1 RM); 50%-1 RM, 75%-1 RM, 90%-1 RM, and 110%-1 RM. the total volume (sets x reps x load) of the exercise was equalized. the lipid profile (Triglycerides [TG], HDL-cholesterol [HDL-c], LDL-cholesterol, and Total cholesterol) was determined at rest and after 1, 24, 48 and 72 h of resistance exercise.Results: the 75%-1 RM group demonstrated greater TG reduction when compared to other groups (p < 0.05). Additionally, the 110%-1 RM group presented an increased TG concentration when compared to 50% and 75% groups (p = 0.01, p = 0.01, respectively). HDL-c concentration was significantly greater after resistance exercise in 50%-1 RM and 75%-1 RM when compared to 110%-1 RM group (p = 0.004 and p = 0.03, respectively). Accordingly, the 50%-1 RM group had greater HDL-c concentration than 110%-1 RM group after 48 h (p = 0.05) and 72 h (p = 0.004), respectively. Finally, the 50% group has showed lesser LDL-c concentration than 110% group after 24 h (p = 0.007). No significant difference was found in Total Cholesterol concentrations.Conclusion: These results indicate that the acute resistance exercise may induce changes in lipid profile in a specific-intensity manner. Overall, low and moderate exercise intensities appear to be promoting more benefits on lipid profile than high intensity. Long term studies should confirm these findings.Univ São Paulo, Inst Biomed Sci, Mol Biol Cell Grp, Dept Cell & Dev Biol, BR-05508 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Physiol, Div Nutr Physiol, São Paulo, BrazilUniFIEO, Dept Biol Sci & Hlth, São Paulo, BrazilUniv São Paulo, Phys Educ & Sport Sch, Lab Appl Nutr & Metab, BR-05508 São Paulo, BrazilMackenzie Presbiterian Univ, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Physiol, Div Nutr Physiol, São Paulo, BrazilWeb of Scienc