Hormonal alteration in obese adolescents with eating disorder: Effects of multidisciplinary therapy
- Carnier, June
- Lofrano, Mara Cristina
- Prado, Wagner Luiz do
- Caranti, Danielle Arisa
- Piano, Aline de
- Tock, Lian
- Nascimento, Claudia Maria da Penha Oller do
- Oyama, Lila Missae
- Mello, Marco Tulio de
- Tufik, Sergio
- Dâmaso, Ana Raimunda
DOIAbstract
Background/Aims: Ghrelin and leptin play important roles in the physiopathology of eating disorders, starting generally in infancy and adolescence. the aim of this study was to evaluate the effects of multidisciplinary short-term therapy on ghrelin and leptin concentrations, bulimia nervosa symptoms, binge eating disorder symptoms, body composition, and visceral and subcutaneous fat in obese adolescents. Methods: Twenty obese adolescents with simple obesity (BMI > 95th percentile, 36.93 +/- 4.14, CDC) were submitted to multidisciplinary ( nutrition, psychology, exercise and clinical) therapy. Plasma ghrelin and leptin concentrations were measured by radioimmunoassay. Bulimic and binge eating behaviors were measured by the Bulimic Investigat...
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