Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience
- Barsottini, Orlando G. P.
- Ferraz, Henrique B.
- Maia, Antonio C. M.
- Silva, Carlos J.
- Rocha, Antonio J.
DOIAbstract
Background: the objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging. Methods: We included 14 consecutive patients with PD (9) or PSP (5). These measures included the third ventricle, midbrain diameter, quadrigeminal plate, brainstem volumetry, and interpeduncular angle. Results: Patients with PSP presented enlargement of third ventricle (100% vs. 33%), lower midbrain diameter (mean 13.2 +/- 1.7 mm vs. 16.5 +/- 1.7 mm) and thinning of the quadrigeminal plate (mean 2.7 +/- 0.3 mm vs. 3.6 +/- 0.3 mm) in comparison with PD. Conclusions: Characteristic findings on MRI may help to differentiate PD from PSP. (C) 2006 Elsevier B.V. All rights reserved.Universidade Federal de São Paulo, Dept Ne...
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