Driven by the use cases of PubChemRDF and SCAIView, we have developed a first community-based clinical trial ontology (CTO) by following the OBO Foundry principles. CTO uses the Basic Formal Ontology (BFO) as the top level ontology and reuses many terms from existing ontologies. CTO has also defined many clinical trial-specific terms. The general CTO design pattern is based on the PICO framework together with two applications. First, the PubChemRDF use case demonstrates how a drug Gleevec is linked to multiple clinical trials investigating Gleevec’s related chemical compounds. Second, the SCAIView text mining engine shows how the use of CTO terms in its search algorithm can identify publications referring to COVID-19-related clinical trials...
BACKGROUND: The increasing use of common data elements (CDEs) in numerous research projects and clin...
Semantic interoperability is essential to facilitate efficient collaboration in heterogeneous multi-...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
Driven by the use cases of PubChemRDF and SCAIView, we have developed a first community-based clinic...
AbstractClinical research includes a wide range of study designs from focused observational studies ...
With the novel COVID-19 pandemic disrupting and threatening the lives of millions, researchers and c...
With the novel COVID-19 pandemic disrupting and threatening the lives of millions, researchers and c...
Current COVID-19 pandemic and previous SARS/MERS outbreaks have caused a series of major crises to g...
We developed an ontology-based system for the de-sign and integration of clinical trial data managem...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
The desideratum of semantic interoperability has been intensively discussed in medical informatics c...
BACKGROUND: The increasing use of common data elements (CDEs) in numerous research projects and clin...
Semantic interoperability is essential to facilitate efficient collaboration in heterogeneous multi-...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
Driven by the use cases of PubChemRDF and SCAIView, we have developed a first community-based clinic...
AbstractClinical research includes a wide range of study designs from focused observational studies ...
With the novel COVID-19 pandemic disrupting and threatening the lives of millions, researchers and c...
With the novel COVID-19 pandemic disrupting and threatening the lives of millions, researchers and c...
Current COVID-19 pandemic and previous SARS/MERS outbreaks have caused a series of major crises to g...
We developed an ontology-based system for the de-sign and integration of clinical trial data managem...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...
The desideratum of semantic interoperability has been intensively discussed in medical informatics c...
BACKGROUND: The increasing use of common data elements (CDEs) in numerous research projects and clin...
Semantic interoperability is essential to facilitate efficient collaboration in heterogeneous multi-...
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely d...